A study finds Covid spike protein impedes adaptive immunity and DNA repair in vitro.
DNA repair guards against the development of a very wide range of degenerative conditions and also prevents rapid chain reactions among those on the brink of physiological instability as a result of comorbidities including hidden imbalances.
This raises big questions about the degrading effects of Covid vaccines.
This is the smoking gun of vaccine safety.
Crucially this completely undermines any justification for vaccine mandates.
Also the whole lax voluntary vaccine adverse effects reporting system needs to be immediately upgraded and put on full alert.
A much wider range of adverse effects which had previously been dismissed as unrelated to vaccines needs to be retrospectively included in reporting.
The roll out of vaccines for the young needs to be put on hold immediately.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy.
Adaptive immunity plays a crucial role in fighting against SARS–CoV–2 infection and directly influences the clinical outcomes of patients.
Clinical studies have indicated that patients with severe COVID–19 exhibit delayed and weak adaptive immune responses; however, the mechanism by which SARS–CoV–2 impedes adaptive immunity remains unclear.
Here, by using an in vitro cell line, we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity.
Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.
Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.
Read the full text here: SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
