Forty years ago the first varieties of genetically modified crops were planted in open fields in the US. Ever since there has been a sustained popular movement to call for these to be banned or at the very least contained and labelled in shops. Today, battles continue to be fought with legislators and regulators across the world in the face of a new strategy that has been developed by the agrichemical/biotechnology industry. This falsely suggests that GM crops produced via CRISPR gene editing are indistinguishable from their natural counterparts and therefore can be fast tracked and exempt from labelling in supermarkets. The HSNO (Hazardous Substances and New Organisms) and ACVM (Agricultural Chemicals and Veterinary Medicines) Amendment Bills are currently before the NZ parliament to this effect. As you probably know, many groups have been lobbying and fighting to prevent its passage, but the economic power of the biotech lobby and their employment of manipulative PR methods is threatening to overwhelm any caution.
The GM crops battle still appears to be the frontline fight, but over the forty years since their first use, the narrowly focused effort to contain them has been quietly bypassed through a proliferation of biosynthetic products produced using gene technologies which have largely escaped public notice. These ubiquitous products are now dominating the preparation of food, cosmetics, medicine, pest control, bio textiles, home products and the environment. They have largely been exempt from meaningful regulation and safety testing. As a result, almost without our knowledge, we are being assailed on all sides by genetically active micro compounds which have the potential to affect our health. Therefore our efforts to oppose deregulation of biotechnology need to be significantly broadened, otherwise we are in danger of being overwhelmed by risky gene technology in every field of life.
Recently we issued a report “A dirty secret exposed: Cosmetics and women’s cancer risk”. In this we detailed the proliferation of genetically synthesised ingredients in cosmetics. We drew attention to a great number of cosmetic ingredients produced using gene based batch fermentation. We mentioned one in particular that is widely used and currently being vigorously advertised as a miraculous anti-ageing skin treatment—hyaluronic acid. The potential dangers of this compound were amply illustrated last week when a wealthy influencer died after undergoing a penis enlargement procedure in Thailand involving an injection of hyaluronic acid. The lurid details are contained in an article in the UK Daily Mail. The coroner’s report reveals the medical details of his death. He suffered a pulmonary embolism (a clot in a blood vessel in his lungs) within hours of the injection. An autopsy revealed that hyaluronic acid had migrated to his lungs and contributed to the clot.
Professor Vaibhav Modgil, an NHS consultant urological surgeon from Manchester, warned that injections of Hyaluronic acid are dangerous. He reported cases of men coming to hospital with their skin sloughing off. Other cases of embolism have also occurred, illustrating how biosynthesised compounds widely used in the cosmetic enhancement industry can be highly mobile in physiological systems, migrating to organs where they can seed serious health issues which may appear immediately or slowly over time. Cosmetic synthetics need not actually be injected to cause problems. Our skin is porous, ensuring that topically applied cosmetic ingredients can cause problems in organs distant from their application points.
How on earth did synthetically produced hyaluronic acid come to be regarded as a miracle cure for ageing?
The new generation of GM biosynthetics are escaping regulation and testing even if there are recorded examples of severe health outcomes. No one is looking carefully at the risks, merely assuming safety and advertising supposed benefits without adequate testing.
Hyaluronic acid is just one example of thousands of genetically active synthetic compounds being introduced in almost every area of life that we are increasingly exposed to and encouraged to use. These are replacing traditional natural ingredients and materials known to be safe. In some cases these are being quietly substituted and in others saturation advertising almost creates an illusion of need, as if life will come to an end if we don’t participate.
Gene bending synthetic residues in food
You may wonder why the taste of some fruit we buy in the supermarket doesn’t seem to be as satisfying as it used to be. In 2021, there was a major shift in fruit treatment aimed at improving storage and prolonging shelf life. 1-Methylcyclopropene (1-MCP) is a synthetic chemical which inhibits ripening in storage. In 2021 it was approved for pre-harvest spraying. In New Zealand it is now sprayed in orchards to manage harvest timing and preserve fruit appearance under the brand name Harvesta.
1-MCP alters gene expression in fruit in numerous ways. It binds permanently to ethylene receptors, down-regulating or suppressing the expression of numerous ripening genes. It also up-regulates patterns of gene expression that can affect flavour and scent. It can work differently in different fruit species. 1-MCP is regarded as largely harmless for humans because we have no ethylene receptors and because 1-MCP is regulated to be used in small quantities, although residue levels are not actually tested. However it is known to cause skin and eye irritation, therefore it does have specific toxic effects on humans whose long term consequences are unknown. The use of pre-harvest 1-MCP sprays has increased the incidence of blue mould and rapid decay in domestic fridges, because it suppresses the disease defence mechanisms of fruit. In other words, it suppresses the immune system mechanisms of fruit.
1-MCP is just another of thousands of synthetic chemicals being routinely added to the food chain and pumped into the environment which affect genetic expression. As the incidence of cancers and autoimmune illness illnesses continues to increase, we have to ask some hard questions about what is causing this epidemic. If you want to avoid exposure to 1-MCP, eat organic fruit or go to your local farmers market to source spray free products. Organic standards ban its use. Instead, commercially produced organic apples for example are stored in controlled temperature, moisture and low oxygen environments to ensure they can be shipped and sold over a longer season without the use of synthetic chemicals. Which just goes to show that there is no compelling reason to use 1-MCP, there are natural alternatives available for all fruit and vegetables. Organic apples may not always look superficially perfect, but they taste great.
Our physiology functions as a coordinated holistic system. Every part is essential to the whole and the whole is essential to every part. To illustrate the dangers of editing genes or altering gene expression. Imagine a jigsaw where just one piece from another jigsaw gets swapped into the box. The novel piece has the wrong colour, size and shape. The holistic value of the original picture can no longer be reproduced. If the novel piece is forced into a location it upsets the continuity of the picture which immediately sticks out to the eye. In the same way, novel genetic sequences contain information and initiate functions that don’t fit with the holistic uniform function of the individual recipient’s genome. They can be forced into a location in DNA through biotech interventions like CRISPR, but due to the complexity of DNA, it is known that this will cause unpredictable and undesirable mutagenic effects.
You can find out more on this topic at our Substack channel where we concentrate on legacy articles and fundamental principles. Last week for example we published a Substack article entitled “Biotechnology is dismantling the fundamental unity of life” which explores the closing theme of today’s article in more detail and depth. This article reports that more than 6,000 trials of gene altering medicines and vaccines are currently underway around the globe. It examines newly published evidence that gene modification can alter our personality and the way we think and perceive. We encourage you to visit and use the embedded link to subscribe to our Substack channel. There is no charge and it complements the up to date news we publish at the Hatchard Report with background principles of life which inform our writing and research.
We want to thank you for your continuing support. As biotechnology encroaches on more and more aspects of our daily life, it is important to keep up to date so that we can make the right choices that will protect our health and well being.



